As the advancement in optical microscopy has pushed our understanding about science towards thinner, deeper, and faster, the quality and complexity of large-volume images generated from these state-of-art microscopes preclude conventional visual and manual analysis. Our lab focused on the data-driven image analysis by integrating the cyberinfrastructure and the advanced computational tools.
Supported by IU's world-leading computational infrastructure, our research integrates multidisciplinary approaches, including instrumentation, programming, and simulations, to quantitatively characterize images in space and time. With the development of imaging hardware and software, we are particularly interested in the fundamental questions in science and engineering. For example, we use fluorescent imaging system to investigate the spatiotemporal dynamics, mechanics, and landscape of individual keynote molecules or proteins in the live cell. In addition, we also work with other collaborators to investigate the light-matter interaction at nanoscale, seeking for scalable non-conventional light source and novel materials for quantum computing.
